Antifungal agents. VI. In vitro antifungal activities of halobenzoyl esters of cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3- dioxolan-4-yl]carbinols.

Abstract Text

The synthesis and the in vitro antifungal activities against Candida albicans and Candida spp of a number of halobenzoyl esters of cis- and trans- [2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan -4- yl]carbinols is reported. Some new imidazoles were found more active than ketoconazole and sometimes as potent as bifonazole against Candida albicans. All derivatives were found scarcely active against Candida spp.

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2016-09-02 11:37:28

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Citation:- Stefancich G, Silvestri G, Pagnozzi G, Artico G, Retico G, Apuzzo G, .Antifungal agents. VI. In vitro antifungal activities of halobenzoyl esters of cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3- dioxolan-4-yl]carbinols. Farmaco (Società chimica italiana : 1989) 1993-Aug;48()1103-12 DOI:



Details of Journal

Journal Title - Farmaco (Società chimica italiana : 1989)

ISSN - 0014-827X

Volume - 48

Issue - 8

Publish date - 1993-Aug

Language - eng

Country - ITALY


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