Bacteriophage-resistant mutants of Escherichia coli K12 with altered lipopolysaccharide. Studies with concanavalin A.

Abstract Text

Three classes of mutants of Escherichia coli K12, isolated by selection for resistance to lipopolysaccharide-specific bacteriophages, were agglutinated by Concanavalin A which is presumed to interact with the lipopolysaccharide component of the outer membrane. Wheat germ and soy bean agglutinins did not agglutinate the parent or mutant strains. The adsorption of certain bacteriophages was also inhibited by Concanavalin A. The pattern of inhibition of adsorption of bacteriophages suggests that non-specific masking of receptors may occur, as well as specific masking of terminal glucose residues. Although bacteria were agglutinated by Concanavalin A, the permeability of the outer membrane seemed unaffected.

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2016-09-01 03:46:06

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Citation:- Picken RN, Beacham RN, .Bacteriophage-resistant mutants of Escherichia coli K12 with altered lipopolysaccharide. Studies with concanavalin A. Journal of general microbiology 1977-Oct;102()319-26 DOI:



Details of Journal

Journal Title - Journal of general microbiology

ISSN - 0022-1287

Volume - 102

Issue - 2

Publish date - 1977-Oct

Language - eng

Country - ENGLAND


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